Binding characterization of N ‐(2‐chloro‐5‐thiomethylphenyl)‐ N ′‐(3‐[ 3 H] 3 methoxy phenyl)‐ N ′‐methylguanidine ([ 3 H] GMOM ), a non‐competitive N ‐methyl‐D‐aspartate ( NMDA ) receptor antagonist
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چکیده
منابع مشابه
Synthesis of a carbon-14 analogue of N-(aryl-methyl)-3-phenyl-acryl amidine-[carboxy-14C] and its derivatives as NR2B-selective NMDA receptor antagonist
Four amidine NR2B-selective NMDA receptor antagonists, N-( 2-methoxy benzyl) -3-phenyl-acrylamidine, N-[diduterio(2-methoxyphenyl) methyl]-3-phenyl-acrylamidine, N-benzyl-3-phenyl-acryl amidine and N-[diduterio(phenyl)methyl]-3-phenyl-acrylamidine, all fourlabeled with carbon-14 in the 1-position, have been synthesized as part of 5-step sequence fromBa14CO3.
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ژورنال
عنوان ژورنال: Pharmacology Research & Perspectives
سال: 2019
ISSN: 2052-1707,2052-1707
DOI: 10.1002/prp2.458